The sativa strain tends to be an uplifting, happy high, with minimal body feel.
The indica strain tends to be a full-body, relaxing high. The indica strain will affect physical abilities more than mental ones, unlike sativa
The hybrid strain is an intermediate between the other two strains. It can provide both an uplifting mind feel, with a relaxing body feel. However, these strains lean towards either being a sativa dominant or indica dominant.